Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 3/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16383761 | 1.00 | SIRT6 (0.45) | SIRT6SIRT1FOLH1GSRGNAI3 | |
| SCHEMBL14064829 | 0.94 | SIRT6 (0.40) | SIRT6SIRT1FOLH1GSRGNAI3 | |
| SCHEMBL15834023 | 0.89 | FOLH1 (0.45) | SIRT6SIRT1FOLH1GSRGNAI3 | |
| SCHEMBL17642078 | 0.86 | GABRR1 (0.37) | SIRT6SIRT1FOLH1DPP8DPP9 | |
| SCHEMBL17050165 | 0.85 | SIRT6 (0.50) | SIRT6SIRT1FOLH1GSRGNAI3 | |
| SCHEMBL2151319 | 0.85 | FOLH1 (0.57) | SIRT6SIRT1FOLH1GSRSLC6A5 | |
| SCHEMBL12304647 | 0.85 | SIRT6 (0.49) | SIRT6SIRT1FOLH1GSRGNAI3 | |
| SCHEMBL2151316 | 0.85 | FOLH1 (0.57) | SIRT6SIRT1FOLH1GSRSLC6A5 | |
| SCHEMBL14820006 | 0.84 | MMP3 (0.43) | SIRT6SIRT1 | |
| Ammonia Solution, Strong SCHEMBL4951257 | 0.83 | FOLH1 (0.56) | SIRT6SIRT1FOLH1GSRSLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519001-B2 | PURIFIED gp120 COMPOSITION RETAINING NATURAL CONFORMATION | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2007-12-19 | — | — | EP | disclosed |