Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PER2 | O15055 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563401 | 1.00 | CA1 (0.51) | CA1CA2LMNACA12CA3 | |
| SCHEMBL15720166 | 1.00 | CA1 (0.51) | CA1CA2LMNACA12CA3 | |
| SCHEMBL24644832 | 1.00 | CA1 (0.51) | CA1CA2LMNACA12CA3 | |
| SCHEMBL24252534 | 1.00 | CA1 (0.51) | CA1CA2LMNACA12CA3 | |
| SCHEMBL2513350 | 0.90 | LMNA (0.46) | CA1CA2LMNACA12CA3 | |
| SCHEMBL562012 | 0.89 | LMNA (0.50) | CA1CA2LMNACA12CA3 | |
| SCHEMBL563053 | 0.89 | LMNA (0.50) | CA1CA2LMNACA12CA3 | |
| SCHEMBL563979 | 0.89 | LMNA (0.50) | CA1CA2LMNACA12CA3 | |
| SCHEMBL563974 | 0.88 | LMNA (0.49) | CA1CA2LMNACA12CA3 | |
| Brivaracetam SCHEMBL122081 | 0.88 | CA1 (0.49) | CA1CA2LMNACA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141002-A1 | CO-CRYSTALS OF PYRROLIDINONES | UCB PHARMA, S.A. (BE) | 2007-12-13 | — | — | WO | disclosed |