Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 11/20 | 0.45 |
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14343664 | 0.86 | EPHX1 (0.55) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14342717 | 0.80 | EPHX1 (0.50) | EPHX1EPHX2RAB9ASMN1; SMN2MAPT | |
| SCHEMBL14343076 | 0.77 | SMN1; SMN2 (0.50) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14343558 | 0.77 | SMN1; SMN2 (0.50) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14342817 | 0.76 | EPHX1 (0.45) | EPHX1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL14343158 | 0.75 | EPHX1 (0.61) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14342803 | 0.75 | EPHX1 (0.54) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12196165 | 0.74 | EPHX1 (1.00) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14343795 | 0.74 | RAB9A (0.62) | EPHX1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL20589924 | 0.73 | EPHX1 (0.97) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007150011-A2 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |