Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5878378 | 0.77 | ALDH1A1 (0.50) | HTTTSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL16644578 | 0.71 | ALDH1A1 (0.65) | HTTUSP2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL22279732 | 0.71 | HTT (0.80) | HTTUSP2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL19387118 | 0.71 | HTT (0.80) | HTTUSP2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL15289758 | 0.71 | HTT (0.80) | HTTUSP2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL10731583 | 0.71 | HTT (0.80) | HTTUSP2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL15967718 | 0.71 | HTT (0.80) | HTTUSP2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL13528309 | 0.70 | ALDH1A1 (0.62) | HTTUSP2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL13528445 | 0.70 | ALDH1A1 (0.62) | HTTUSP2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL16039625 | 0.67 | USP2 (0.44) | HTTUSP2TSHRHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144200-A1 | PROCESS FOR THE COVALENT COUPLING OF TWO MOLECULES BY MEANS OF A DIELS-ALDER REACTION WITH INVERSE ELECTRON REQUIREMENT | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2007-12-21 | — | — | WO | disclosed |