SCHEMBL14344685

SCHEMBL14344685

O=C(Nc1ccc2c(=O)[nH][nH]c2c1)c1cc2ccccc2cc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 7/20 0.56
▸ RAB9A P51151 6/20 0.56
▸ MEN1 O00255 6/20 0.56
▸ NPC1 O15118 5/20 0.56
▸ POLB P06746 4/20 0.56
▸ CASP3 P42574 1/20 0.54
▸ SENP7 Q9BQF6 1/20 0.54
▸ SENP6 Q9GZR1 1/20 0.54
▸ PLG P00747 3/20 0.53
▸ KLK1 P06870 2/20 0.53
▸ KLK6 Q92876 2/20 0.53
▸ MAPT P10636 3/20 0.51
▸ MAPK1 P28482 1/20 0.51
▸ APOBEC3A P31941 1/20 0.51
▸ APOBEC3G Q9HC16 1/20 0.51
▸ PLAU P00749 2/20 0.50
▸ F2 P00734 1/20 0.50
▸ F10 P00742 1/20 0.50
▸ PLAT P00750 1/20 0.50
▸ TNF P01375 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30081451 0.80 MAPT (0.64) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL1737847 0.80 MAPT (0.64) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL5426499 0.79 KMT2A (0.84) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL29575344 0.78 RAB9A (0.77) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL2681852 0.78 RAB9A (0.77) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL12521448 0.77 RAB9A (0.70) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL12519865 0.76 KMT2A (0.65) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL14344682 0.76 MEN1 (0.52) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL15478030 0.75 KMT2A (0.77) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL30084384 0.75 MEN1 (0.77) KMT2ARAB9AMEN1NPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7309552-B2 Containing the reaction product of a dibenzo [a,c]phenadine-2,7-bisdiazonium salt and a coupler such as N-benzyl-2-hydroxy-7,8-naphthalic acid imide; stilbene charge transport material; 1alkylidene-2,3-diphenylindene acceptor; biphenol; copolycarbonate containing arylamine groups; highly durable RICOH COMPANY, LTD. (JP) 2007-12-18 — — US disclosed
US-7309552-B2 Containing the reaction product of a dibenzo [a,c]phenadine-2,7-bisdiazonium salt and a coupler such as N-benzyl-2-hydroxy-7,8-naphthalic acid imide; stilbene charge transport material; 1alkylidene-2,3-diphenylindene acceptor; biphenol; copolycarbonate containing arylamine groups; highly durable RICOH COMPANY, LTD. (JP) 2007-12-18 — — US disclosed
US-7175958-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same RICOH COMPANY, LTD. (JP) 2007-02-13 — — US disclosed
US-7175958-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same RICOH COMPANY, LTD. (JP) 2007-02-13 — — US disclosed
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