SCHEMBL14344704

SCHEMBL14344704

O=C(Nc1ccccc1)c1cc2ccc3c([nH]c4ccc5ccccc5c43)c2cc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.61
▸ KMT2A Q03164 4/20 0.61
▸ KDM4E B2RXH2 2/20 0.61
▸ MAPT P10636 2/20 0.61
▸ CACNA1B Q00975 1/20 0.61
▸ APBA1 Q02410 1/20 0.61
▸ MPL P40238 4/20 0.55
▸ CDK4 P11802 1/20 0.45
▸ CCND1 P24385 1/20 0.45
▸ NPC1 O15118 3/20 0.44
▸ RAB9A P51151 3/20 0.44
▸ POLB P06746 1/20 0.44
▸ GAA P10253 1/20 0.43
▸ CASP3 P42574 1/20 0.43
▸ SENP7 Q9BQF6 1/20 0.43
▸ SENP6 Q9GZR1 1/20 0.43
▸ PLG P00747 3/20 0.42
▸ F2 P00734 1/20 0.42
▸ F10 P00742 1/20 0.42
▸ PLAU P00749 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14344726 0.88 MEN1 (0.64) MEN1KMT2AKDM4EMAPTCACNA1B
SCHEMBL175806 0.86 KMT2A (0.78) MEN1KMT2AKDM4EMAPTCACNA1B
SCHEMBL9728924 0.82 KDM4E (0.63) MEN1KMT2AKDM4EMAPTCACNA1B
SCHEMBL10719334 0.79 MEN1 (0.80) MEN1KMT2AKDM4EMAPTCACNA1B
SCHEMBL10987424 0.78 KMT2A (0.79) MEN1KMT2AKDM4EMAPTCACNA1B
SCHEMBL9354492 0.77 KMT2A (0.70) MEN1KMT2AKDM4EMAPTCACNA1B
SCHEMBL5820002 0.76 MEN1 (1.00) MEN1KMT2AKDM4EMAPTCACNA1B
SCHEMBL29405509 0.76 MEN1 (1.00) MEN1KMT2AKDM4EMAPTCACNA1B
SCHEMBL10989850 0.76 KMT2A (0.75) MEN1KMT2AKDM4EMAPTCACNA1B
SCHEMBL20739018 0.76 MAPT (0.69) MEN1KMT2AKDM4EMAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7309552-B2 Containing the reaction product of a dibenzo [a,c]phenadine-2,7-bisdiazonium salt and a coupler such as N-benzyl-2-hydroxy-7,8-naphthalic acid imide; stilbene charge transport material; 1alkylidene-2,3-diphenylindene acceptor; biphenol; copolycarbonate containing arylamine groups; highly durable RICOH COMPANY, LTD. (JP) 2007-12-18 — — US disclosed
US-7309552-B2 Containing the reaction product of a dibenzo [a,c]phenadine-2,7-bisdiazonium salt and a coupler such as N-benzyl-2-hydroxy-7,8-naphthalic acid imide; stilbene charge transport material; 1alkylidene-2,3-diphenylindene acceptor; biphenol; copolycarbonate containing arylamine groups; highly durable RICOH COMPANY, LTD. (JP) 2007-12-18 — — US disclosed
US-7175958-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same RICOH COMPANY, LTD. (JP) 2007-02-13 — — US disclosed
US-7175958-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same RICOH COMPANY, LTD. (JP) 2007-02-13 — — US disclosed
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