Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.41 |
| ▸ | KDM7A | Q6ZMT4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.39 |
| ▸ | KDM6B | O15054 | 2/20 | 0.39 |
| ▸ | KDM5C | P41229 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 11/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14344904 | 0.86 | LMNA (0.42) | LMNAALDH1A1 | |
| Succinic Acid SCHEMBL27634156 | 0.82 | LMNA (0.52) | PHF8KDM2AKDM7ALMNASLC15A2 | |
| SCHEMBL440142 | 0.80 | PHF8 (0.44) | PHF8KDM2AKDM7ALMNASLC15A2 | |
| SCHEMBL3175734 | 0.79 | NOS3 (0.52) | PHF8KDM2AKDM7AEGLN1KDM6B | |
| SCHEMBL27383435 | 0.77 | PHF8 (0.39) | PHF8KDM2AKDM7AEGLN1KDM6B | |
| SCHEMBL1869025 | 0.77 | PHF8 (0.46) | PHF8KDM2AKDM7ALMNASLC15A2 | |
| SCHEMBL12927432 | 0.76 | PHF8 (0.41) | PHF8KDM2AKDM7ALMNASLC15A2 | |
| SCHEMBL9216352 | 0.75 | — | — | |
| SCHEMBL8643901 | 0.73 | PHF8 (0.43) | PHF8KDM2AKDM7ALMNAEGLN1 | |
| SCHEMBL19170270 | 0.73 | PHF8 (0.43) | PHF8KDM2AKDM7ALMNAEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |