SCHEMBL14344741

SCHEMBL14344741

CC(=N)N1CCC(N(C)C)CC1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 2/20 0.48
CPN1 P15169 1/20 0.40
CPB2 Q96IY4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
CDYL Q9Y232 1/20 0.33
CDY1; CDY1B Q9Y6F8 1/20 0.33
HDAC4 P56524 1/20 0.31
USP5 P45974 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13349247 0.80 L3MBTL3 (0.47) L3MBTL3CPN1CPB2L3MBTL1
SCHEMBL22699009 0.77 L3MBTL3 (0.48) L3MBTL3L3MBTL1CDYLCDY1; CDY1BHDAC4
SCHEMBL4550247 0.77 L3MBTL3 (0.58) L3MBTL3L3MBTL1
SCHEMBL22878132 0.76 L3MBTL3 (0.56) L3MBTL3L3MBTL1CDYLCDY1; CDY1BHDAC4
SCHEMBL27781047 0.74 L3MBTL3 (0.60) L3MBTL3L3MBTL1CDYLCDY1; CDY1BHDAC4
SCHEMBL14344738 0.74 CPN1 (0.41) CPN1CPB2
SCHEMBL3318797 0.73 CPN1 (0.47) CPN1CPB2
SCHEMBL1149395 0.73 PHGDH (0.48) CPN1CPB2
SCHEMBL3318800 0.73 CPN1 (0.43) CPN1CPB2L3MBTL1
SCHEMBL14344826 0.73 CPN1 (0.43) CPN1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4180061-A1 ANTHRACYCLINE DERIVATIVE LINKER REAGENTS, ANTIBODY-DRUG CONJUGATES AND METHODS Nerviano Medical Sciences S.r.l. (IT) 2023-05-17 EP disclosed
US-7312235-B2 Benzamide inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-12-25 US disclosed
US-7312235-B2 Benzamide inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-12-25 US disclosed