Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.33 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25633197 | 0.87 | L3MBTL3 (0.42) | L3MBTL3L3MBTL1 | |
| SCHEMBL4550247 | 0.77 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1 | |
| SCHEMBL14344741 | 0.77 | L3MBTL3 (0.48) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BHDAC4 | |
| SCHEMBL13328192 | 0.77 | L3MBTL3 (0.44) | L3MBTL3L3MBTL1CDYLCDY1; CDY1B | |
| SCHEMBL23916097 | 0.76 | L3MBTL3 (0.31) | L3MBTL3 | |
| SCHEMBL425964 | 0.76 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BHDAC4 | |
| SCHEMBL22878132 | 0.76 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BHDAC4 | |
| SCHEMBL25663931 | 0.75 | PIK3CD (0.49) | L3MBTL3 | |
| SCHEMBL24244835 | 0.75 | ALDH1A1 (0.34) | L3MBTL3 | |
| SCHEMBL27781047 | 0.74 | L3MBTL3 (0.60) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3741756-A1 | PYRIDONE-PYRIMIDINE DERIVATIVE ACTING AS KRASG12C MUTEIN INHIBITOR | Medshine Discovery Inc. (CN) | 2020-11-25 | — | — | EP | disclosed |