Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.52 |
| ▸ | CA1 | P00915 | 14/20 | 0.52 |
| ▸ | CA12 | O43570 | 13/20 | 0.52 |
| ▸ | CA9 | Q16790 | 13/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5646084 | 0.86 | CA2 (0.55) | CA2CA1CA12CA9STAT3 | |
| SCHEMBL3480083 | 0.78 | CA2 (0.44) | CA2CA1CA12CA9CA4 | |
| SCHEMBL27954273 | 0.76 | CA1 (0.55) | CA2CA1CA12CA9STAT3 | |
| SCHEMBL4802533 | 0.75 | CA2 (0.53) | CA2CA1CA12CA9CA4 | |
| SCHEMBL3480416 | 0.75 | MAP3K5 (0.35) | CA2CA1CA12CA9MAOA | |
| SCHEMBL28168244 | 0.75 | CA1 (0.54) | CA2CA1CA12CA9CA4 | |
| SCHEMBL23254983 | 0.74 | APP (0.57) | CA2CA1CA12CA9CA4 | |
| SCHEMBL17785542 | 0.73 | CA2 (0.64) | CA2CA1CA12CA9CA4 | |
| SCHEMBL3480050 | 0.72 | CA2 (0.49) | CA2CA1CA12CA9CA4 | |
| SCHEMBL13032506 | 0.72 | TRPA1 (0.43) | CA2CA1MAOAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007139729-A1 | NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE | MERCK & CO., INC. (US) | 2007-12-06 | — | — | WO | disclosed |