Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | CALML3 | P27482 | 1/20 | 0.59 |
| ▸ | SDHA | P31040 | 1/20 | 0.59 |
| ▸ | MIF | P14174 | 9/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468825 | 1.00 | MAOB (0.59) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7463009 | 0.92 | MIF (0.53) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7471612 | 0.89 | MAOA (0.59) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7469527 | 0.89 | MIF (0.50) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7471239 | 0.89 | MIF (0.50) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7469138 | 0.88 | MAOA (0.48) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7473717 | 0.87 | MIF (0.48) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7467858 | 0.87 | MIF (0.48) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL27880820 | 0.86 | MIF (0.47) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL27684361 | 0.86 | MIF (0.47) | MAOBMAOALMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138381-A2 | PHOSPHONATED OXAZOLIDINONES AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | TARGANTA THERAPEUTICS INC. (CA) | 2007-12-06 | — | — | WO | disclosed |