SCHEMBL7473717 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	MIF	P14174	16/20	0.48

▸	MAOA	P21397	3/20	0.45

▸	MAOB	P27338	2/20	0.45

▸	LMNA	P02545	1/20	0.45

▸	PTGS1	P23219	1/20	0.45

▸	CALML3	P27482	1/20	0.45

▸	SDHA	P31040	1/20	0.45

▸	RAB9A	P51151	1/20	0.40

▸	HDAC6	Q9UBN7	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7478325	0.91	RAB9A (0.45)	MIFMAOAMAOBLMNAPTGS1
SCHEMBL7463009	0.89	MIF (0.53)	MIFMAOAMAOBLMNAPTGS1
SCHEMBL7468825	0.87	MAOB (0.59)	MIFMAOAMAOBLMNAPTGS1
SCHEMBL14345346	0.87	MAOB (0.59)	MIFMAOAMAOBLMNAPTGS1
SCHEMBL7469527	0.87	MIF (0.50)	MIFMAOAMAOBLMNAPTGS1
SCHEMBL7471612	0.87	MAOA (0.59)	MIFMAOAMAOBLMNAPTGS1
SCHEMBL7471239	0.87	MIF (0.50)	MIFMAOAMAOBLMNAPTGS1
SCHEMBL7467858	0.84	MIF (0.48)	MIFMAOAMAOBLMNAPTGS1
SCHEMBL27880820	0.83	MIF (0.47)	MIFMAOAMAOBLMNAPTGS1
SCHEMBL27684361	0.83	MIF (0.47)	MIFMAOAMAOBLMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1054874-B1	SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS	UPJOHN CO (US)	2002-08-28	—	—	EP	claimed