Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 14/20 | 0.69 |
| ▸ | CDC7 | O00311 | 1/20 | 0.53 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345636 | 0.84 | DHODH (0.65) | PTGDR2CDC7DBF4ALDH1A1CYP1A2 | |
| SCHEMBL4485015 | 0.83 | CDC7 (0.71) | PTGDR2CDC7DBF4SMN1; SMN2KDM4E | |
| SCHEMBL4285011 | 0.79 | RAB9A (0.71) | PTGDR2SMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL27654539 | 0.77 | CDC7 (0.54) | PTGDR2CDC7DBF4SMN1; SMN2NPC1 | |
| SCHEMBL27905931 | 0.77 | SMN1; SMN2 (0.52) | PTGDR2SMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL974859 | 0.76 | CDC7 (0.84) | PTGDR2CDC7DBF4SMN1; SMN2KDM4E | |
| SCHEMBL3894571 | 0.75 | ALDH1A1 (0.68) | CDC7DBF4SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL10268752 | 0.74 | CDC7 (0.51) | PTGDR2CDC7DBF4SMN1; SMN2ALDH1A1 | |
| SCHEMBL11286855 | 0.73 | SMN1; SMN2 (0.54) | PTGDR2CDC7DBF4SMN1; SMN2KDM4E | |
| SCHEMBL14345710 | 0.73 | PTGDR2 (0.55) | PTGDR2SMN1; SMN2RAB9AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | disclosed |