Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14156019 | 0.87 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL14157941 | 0.87 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL14345883 | 0.73 | ALDH1A1 (0.48) | ALDH1A1LMNATSHRCYP3A4TDP1 | |
| SCHEMBL14156080 | 0.73 | ALDH1A1 (0.48) | ALDH1A1LMNATSHRCYP3A4TDP1 | |
| SCHEMBL10644154 | 0.71 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL14518010 | 0.70 | TSHR (0.50) | ALDH1A1LMNATSHRCYP3A4ATM | |
| SCHEMBL14156030 | 0.70 | CYP2C9 (0.42) | ALDH1A1LMNATSHRTDP1CYP2C9 | |
| SCHEMBL13992591 | 0.70 | TSHR (0.50) | ALDH1A1LMNATSHRCYP3A4ATM | |
| SCHEMBL14346232 | 0.70 | TSHR (0.50) | ALDH1A1LMNATSHRCYP3A4ATM | |
| SCHEMBL28967079 | 0.70 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPK1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007149326-A2 | THERMALLY DEVELOPABLE MATERIALS STABILIZED WITH CROWN ETHERS | CARESTREAM HEALTH, INC. (US) | 2007-12-27 | — | — | WO | disclosed |