Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13992591 | 1.00 | TSHR (0.50) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL14518010 | 1.00 | TSHR (0.50) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL14345883 | 0.93 | ALDH1A1 (0.48) | TSHRHCAR2DNM1TP53CYP2C9 | |
| SCHEMBL14156080 | 0.93 | ALDH1A1 (0.48) | TSHRHCAR2DNM1TP53CYP2C9 | |
| SCHEMBL8000911 | 0.90 | TSHR (0.53) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL14157943 | 0.89 | DNM1 (0.50) | TSHRDNM1TP53CYP2C9POLB | |
| SCHEMBL11147631 | 0.85 | TSHR (0.49) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL19834331 | 0.85 | TSHR (0.49) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL17142025 | 0.85 | TSHR (0.49) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL20261950 | 0.84 | TSHR (0.47) | TSHRNAAAHCAR2RAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007149326-A2 | THERMALLY DEVELOPABLE MATERIALS STABILIZED WITH CROWN ETHERS | CARESTREAM HEALTH, INC. (US) | 2007-12-27 | — | — | WO | disclosed |