Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12845918 | 0.86 | PARP1 (0.64) | PARP1 | |
| SCHEMBL12846284 | 0.75 | PARP1 (0.64) | PARP1 | |
| SCHEMBL12846160 | 0.72 | PARP1 (0.65) | PARP1 | |
| SCHEMBL12256417 | 0.67 | PARP1 (1.00) | PARP1 | |
| SCHEMBL29435084 | 0.67 | PARP1 (1.00) | PARP1 | |
| SCHEMBL21160645 | 0.67 | PARP1 (0.74) | PARP1 | |
| SCHEMBL14980870 | 0.65 | PARP1 (1.00) | PARP1 | |
| SCHEMBL21155625 | 0.65 | PARP1 (0.70) | PARP1 | |
| SCHEMBL12845984 | 0.62 | PARP1 (0.49) | PARP1 | |
| SCHEMBL12846279 | 0.61 | PARP1 (0.57) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007149451-A2 | CYCLOALKANOPYRROLOCARBAZOLE DERIVATIVES AND THE USE THEREOF AS PARP, VEGFR2 AND MLK3 INHIBITORS | CEPHALON, INC. (US) | 2007-12-27 | — | — | WO | disclosed |