Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.65 |
| ▸ | DRD3 | P35462 | 13/20 | 0.65 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13630327 | 1.00 | DRD2 (0.65) | DRD2DRD3HTR2A | |
| SCHEMBL13630343 | 0.90 | DRD2 (0.66) | DRD2DRD3HTR2A | |
| SCHEMBL14347022 | 0.90 | DRD3 (0.53) | DRD2DRD3HTR2A | |
| SCHEMBL13630275 | 0.90 | DRD3 (0.53) | DRD2DRD3HTR2A | |
| SCHEMBL17226486 | 0.90 | DRD2 (0.66) | DRD2DRD3HTR2A | |
| SCHEMBL17226506 | 0.90 | DRD2 (0.66) | DRD2DRD3HTR2A | |
| SCHEMBL13630462 | 0.90 | DRD2 (0.66) | DRD2DRD3HTR2A | |
| SCHEMBL13630371 | 0.90 | DRD2 (0.68) | DRD2DRD3 | |
| SCHEMBL13630224 | 0.89 | DRD2 (0.68) | DRD2DRD3 | |
| SCHEMBL14346739 | 0.89 | DRD2 (0.68) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038268-B1 | CARBONYLATED (AZA)CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET SOC CIV (FR) | 2015-11-04 | — | — | EP | disclosed |
| WO-2007148208-A2 | CARBONYLATED (AZA) CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET (FR) | 2007-12-27 | — | — | WO | disclosed |