Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.66 |
| ▸ | DRD3 | P35462 | 13/20 | 0.66 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13630462 | 1.00 | DRD2 (0.66) | DRD2DRD3DRD4MAPTGFER | |
| SCHEMBL13630263 | 0.90 | DRD2 (0.69) | DRD2DRD3DRD4HTR2A | |
| SCHEMBL14346705 | 0.90 | DRD2 (0.65) | DRD2DRD3HTR2A | |
| SCHEMBL13630327 | 0.90 | DRD2 (0.65) | DRD2DRD3HTR2A | |
| SCHEMBL13630275 | 0.88 | DRD3 (0.53) | DRD2DRD3HTR2A | |
| SCHEMBL17226486 | 0.88 | DRD2 (0.66) | DRD2DRD3HTR2A | |
| SCHEMBL14347022 | 0.88 | DRD3 (0.53) | DRD2DRD3HTR2A | |
| SCHEMBL13630343 | 0.88 | DRD2 (0.66) | DRD2DRD3HTR2A | |
| SCHEMBL13630371 | 0.85 | DRD2 (0.68) | DRD2DRD3 | |
| SCHEMBL13629903 | 0.85 | DRD2 (0.66) | DRD2DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038268-B1 | CARBONYLATED (AZA)CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET SOC CIV (FR) | 2015-11-04 | — | — | EP | disclosed |