Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17115183 | 0.81 | GAA (0.44) | SMN1; SMN2ALDH1A1TP53HTTRAB9A | |
| SCHEMBL10991202 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP3A4ALDH1A1TP53TSHR | |
| SCHEMBL30944287 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP3A4ALDH1A1TP53TSHR | |
| SCHEMBL219725 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP3A4ALDH1A1TP53TSHR | |
| SCHEMBL222470 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP3A4ALDH1A1TP53TSHR | |
| SCHEMBL18614481 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP3A4ALDH1A1TP53TSHR | |
| SCHEMBL19753611 | 0.75 | NPC1 (0.47) | SMN1; SMN2RAB9ANQO2GAAMAPK1 | |
| SCHEMBL24175979 | 0.75 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP3A4ALDH1A1TP53TSHR | |
| SCHEMBL1707911 | 0.74 | SMN1; SMN2 (0.68) | SMN1; SMN2CYP3A4ALDH1A1TP53TSHR | |
| SCHEMBL13735781 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP3A4ALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007148093-A1 | ANTIBACTERIAL COMPOSITIONS | PROLYSIS LTD. (GB) | 2007-12-27 | — | — | WO | disclosed |