Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25245500 | 0.81 | SMN1; SMN2 (0.39) | GAASMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL17102374 | 0.81 | NPC1 (0.39) | GAASMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL17115155 | 0.81 | SMN1; SMN2 (0.39) | GAASMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL14347169 | 0.81 | SMN1; SMN2 (0.68) | GAASMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL2171105 | 0.79 | SMN1; SMN2 (0.66) | GAASMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL17102371 | 0.78 | NQO2 (0.49) | GAASMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL19753611 | 0.78 | NPC1 (0.47) | GAASMN1; SMN2NPC1RAB9ANQO2 | |
| SCHEMBL16437413 | 0.72 | SMN1; SMN2 (0.43) | GAASMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL17859545 | 0.72 | RAB9A (0.56) | GAASMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL12046198 | 0.71 | GAA (0.52) | GAASMN1; SMN2NPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119765-B1 | HETEROARYL SYK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2019-07-17 | — | — | EP | disclosed |
| WO-2015140054-A1 | HETEROARYL SYK INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-09-24 | — | — | WO | disclosed |