Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 9/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14347611 | 0.91 | KDM4E (0.48) | ALOX15KMT2ALMNATSHRGAA | |
| SCHEMBL14347617 | 0.88 | GAA (0.47) | ALOX15TP53MEN1KMT2ACYP1A2 | |
| SCHEMBL14347613 | 0.81 | KDM4E (0.49) | KMT2ACYP1A2LMNACYP3A4TSHR | |
| SCHEMBL38652398 | 0.74 | LMNA (0.56) | TP53MEN1KMT2ALMNATSHR | |
| SCHEMBL38652306 | 0.74 | LMNA (0.56) | TP53MEN1KMT2ALMNATSHR | |
| SCHEMBL14347625 | 0.70 | KMT2A (0.43) | MEN1KMT2ACYP1A2LMNACYP3A4 | |
| SCHEMBL14374465 | 0.70 | KMT2A (0.43) | MEN1KMT2ACYP1A2LMNACYP3A4 | |
| SCHEMBL4335836 | 0.70 | ALOX15 (0.58) | ALOX15TP53GAA | |
| SCHEMBL14347607 | 0.69 | MEN1 (0.53) | MEN1KMT2ACYP1A2LMNACYP3A4 | |
| SCHEMBL1880966 | 0.69 | KDM4E (0.65) | KMT2ACYP1A2LMNACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307170-B2 | Epindolidione pigments | CLARIANT FINANCE (BVI) LIMITED (VG) | 2007-12-11 | — | — | US | disclosed |
| US-7307170-B2 | Epindolidione pigments | CLARIANT FINANCE (BVI) LIMITED (VG) | 2007-12-11 | — | — | US | disclosed |