Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27078205 | 0.94 | MEN1 (0.63) | NR4A1NR4A2NR4A3MEN1KMT2A | |
| SCHEMBL21101819 | 0.93 | NR4A1 (0.50) | NR4A1NR4A2NR4A3MEN1KMT2A | |
| SCHEMBL21874210 | 0.93 | MEN1 (0.62) | NR4A1NR4A2NR4A3MEN1KMT2A | |
| SCHEMBL23163539 | 0.90 | MMP1 (0.53) | NR4A1NR4A2NR4A3MEN1KMT2A | |
| SCHEMBL14347696 | 0.88 | MAOB (0.59) | NR4A1NR4A2NR4A3LMNACYP1A2 | |
| SCHEMBL25315317 | 0.87 | NR4A1 (0.53) | NR4A1NR4A2NR4A3LMNACYP1A2 | |
| SCHEMBL10253179 | 0.87 | NR4A1 (0.53) | NR4A1NR4A2NR4A3LMNACYP1A2 | |
| SCHEMBL21874358 | 0.85 | NR4A1 (0.51) | NR4A1NR4A2NR4A3LMNACYP1A2 | |
| SCHEMBL20755014 | 0.85 | NPC1 (0.55) | NR4A1NR4A2NR4A3LMNACYP1A2 | |
| SCHEMBL10083334 | 0.84 | MAOB (0.57) | NR4A2KMT2AMAOBSRD5A2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107266345-A | It is used as (miscellaneous) aryl rings propanamine compounds of LSD1 inhibitor | 奥瑞泽恩基因组学股份有限公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-104203914-B | (hetero) arylcyclopropylamine compounds as LSD1 inhibitors | 奥瑞泽恩基因组学股份有限公司 | 2017-07-11 | — | — | CN | disclosed |
| US-7304081-B2 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION (US) | 2007-12-04 | — | — | US | disclosed |