Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14347698 | 0.88 | NR4A1 (0.57) | MAOBNR4A1NR4A2NR4A3ALOX5 | |
| SCHEMBL20755014 | 0.86 | NPC1 (0.55) | MAOBNR4A1NR4A2NR4A3ALOX5 | |
| SCHEMBL10253179 | 0.84 | NR4A1 (0.53) | MAOBNR4A1NR4A2NR4A3PTGS1 | |
| SCHEMBL27078205 | 0.82 | MEN1 (0.63) | MAOBNR4A1NR4A2NR4A3PTGS1 | |
| SCHEMBL21101819 | 0.82 | NR4A1 (0.50) | MAOBNR4A1NR4A2NR4A3PTGS1 | |
| SCHEMBL21874210 | 0.81 | MEN1 (0.62) | MAOBNR4A1NR4A2NR4A3PTGS1 | |
| SCHEMBL23164194 | 0.81 | NPC1 (0.52) | MAOBNR4A1NR4A2NR4A3PTGS1 | |
| SCHEMBL21961641 | 0.80 | NPC1 (0.49) | MAOBNR4A1NR4A2NR4A3MMP2 | |
| SCHEMBL23972749 | 0.79 | LMNA (0.51) | MAOBNR4A1NR4A2NR4A3PTGS1 | |
| SCHEMBL23163539 | 0.79 | MMP1 (0.53) | MAOBNR4A1NR4A2NR4A3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304081-B2 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION (US) | 2007-12-04 | — | — | US | disclosed |