Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19242638 | 0.98 | KMT2A (0.60) | MEN1KMT2AMAPK1GAAAKR1C1 | |
| SCHEMBL16507031 | 0.95 | KMT2A (0.56) | MEN1KMT2AMAPK1GAAAKR1C1 | |
| Hydrochloric Acid SCHEMBL16507430 | 0.94 | MAPK1 (0.58) | MEN1KMT2AMAPK1GAAAKR1C1 | |
| SCHEMBL19242698 | 0.88 | SMN1; SMN2 (0.62) | MEN1KMT2AMAPK1GAAAKR1C1 | |
| SCHEMBL8353497 | 0.84 | USP2 (0.45) | MEN1KMT2AMAPK1GAALMNA | |
| SCHEMBL8351554 | 0.81 | USP2 (0.45) | MEN1KMT2ALMNAL3MBTL1HSD11B1 | |
| SCHEMBL16523027 | 0.80 | HSD11B1 (0.62) | LMNAHSD11B1HDAC4SMN1; SMN2SIGMAR1 | |
| SCHEMBL19242639 | 0.79 | MEN1 (0.53) | MEN1KMT2AMAPK1GAAAKR1C1 | |
| SCHEMBL5643072 | 0.79 | OPRM1 (0.44) | MEN1KMT2AMAPK1GAALMNA | |
| SCHEMBL8351187 | 0.79 | USP2 (0.46) | MEN1KMT2ALMNAL3MBTL1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017138838-A1 | ARYLCYCLOALKYLAMINE DERIVATIVES EXHIBITING A NEUROPROTECTIVE, ANALGESIC AND ANTIDEPRESSANT EFFECT | АКЦИОНЕРНОЕ ОБЩЕСТВО "ВЕРТЕКС" | 2017-08-17 | — | — | WO | disclosed |
| US-7312214-B2 | 1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-25 | — | — | US | disclosed |