Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 2/20 | 0.44 |
| ▸ | MAX | P61244 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651273 | 0.86 | MYC (0.53) | MERTKMYCMAXALDH1A1HTT | |
| SCHEMBL30068176 | 0.86 | MYC (0.53) | MERTKMYCMAXALDH1A1HTT | |
| SCHEMBL4652551 | 0.84 | MYC (0.44) | MERTKMYCMAXALDH1A1HTT | |
| SCHEMBL15507763 | 0.82 | MYC (0.47) | MERTKMYCMAXALDH1A1HTT | |
| SCHEMBL30870967 | 0.82 | MYC (0.47) | MERTKMYCMAXALDH1A1HTT | |
| SCHEMBL29231882 | 0.81 | MYC (0.50) | MERTKMYCMAXALDH1A1HTT | |
| SCHEMBL31528961 | 0.79 | MYC (0.45) | MERTKMYCMAXALDH1A1HTT | |
| SCHEMBL31326382 | 0.77 | MYC (0.44) | MERTKMYCMAXHTTTXNRD1 | |
| SCHEMBL26646950 | 0.77 | TXNRD1 (0.42) | MERTKMYCMAXALDH1A1HTT | |
| SCHEMBL4653656 | 0.77 | MYC (0.57) | MERTKMYCMAXALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312246-B2 | Proteomimetic compounds and methods | YALE UNIVERSITY (US) | 2007-12-25 | — | — | US | disclosed |