Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.53 |
| ▸ | MAX | P61244 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651273 | 1.00 | MYC (0.53) | MYCMAXKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL29231882 | 0.92 | MYC (0.50) | MYCMAXKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL31326400 | 0.89 | MYC (0.50) | MYCMAXKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL4652551 | 0.86 | MYC (0.44) | MYCMAXALDH1A1MERTKHTT | |
| SCHEMBL14348284 | 0.86 | MERTK (0.47) | MYCMAXALDH1A1MERTKAPP | |
| SCHEMBL30870967 | 0.83 | MYC (0.47) | MYCMAXL3MBTL1ALDH1A1MERTK | |
| SCHEMBL15507763 | 0.83 | MYC (0.47) | MYCMAXL3MBTL1ALDH1A1MERTK | |
| SCHEMBL4652365 | 0.83 | MYC (0.56) | MYCMAXKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL21494712 | 0.80 | PIN1 (0.55) | MYCMAXKDM4EALDH1A1MERTK | |
| SCHEMBL31528961 | 0.80 | MYC (0.45) | MYCMAXL3MBTL1ALDH1A1MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337198-A1 | POLO LIKE KINASE 4 INHIBITORS | Oric Pharmaceuticals, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022240876-A1 | POLO LIKE KINASE 4 INHIBITORS | ORIC PHARMACEUTICALS, INC. (US) | 2022-11-17 | — | — | WO | disclosed |