Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Vanillin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB known ✓ | P27338 | 2/20 | 0.52 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.52 |
| ▸ | TLR9 known ✓ | Q9NR96 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.76 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.76 |
| ▸ | ABAT | P80404 | 1/20 | 0.76 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.76 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vanillin SCHEMBL44060 | 0.94 | ALDH1A1 (0.86) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL28058713 | 0.94 | ALDH1A1 (0.86) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL1943810 | 0.94 | ALDH1A1 (0.86) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL27849261 | 0.92 | ALDH1A1 (0.83) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL10335743 | 0.91 | ALDH1A1 (0.81) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL395732 | 0.89 | ALDH1A1 (0.83) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL27673973 | 0.89 | ALDH1A1 (0.89) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL4411107 | 0.88 | ALDH1A1 (0.76) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL26927685 | 0.88 | ALDH1A1 (0.76) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Vanillin SCHEMBL28655107 | 0.88 | ALDH1A1 (0.81) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114354813-B | Detection method of intestine-strengthening antidiarrheal mixture | 海安市中医院 | 2024-07-12 | — | — | CN | claimed |
| CN-118112164-A | Thin-layer detection method and application of motherwort herb or Chinese herbal preparation | 广东一方制药有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-115508495-B | Identification method of boiled peach kernels in Taohong Siwu decoction | 海南葫芦娃药业集团股份有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-117695364-A | Traditional Chinese medicine composition for strengthening spleen and stomach, preparation method and quality detection method | 北京中研同仁堂医药研发有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-117517494-A | Quality control and detection method of Chinese patent medicine Yunnan girl gold pill | 红云制药(昆明)有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117269372-A | Quality detection method of Zhuang medicine Luo Qianyu cataplasm | 广西中医药大学 | 2023-12-22 | — | — | CN | claimed |
| CN-117007716-A | Thin layer chromatography method for simultaneously identifying different medicinal flavors in decoction for warming channels and preparation thereof | 深圳市中药制造业创新中心有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116219568-B | Antibacterial polypropylene filament and preparation method thereof | 泰州市广源化纺有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-115043790-B | Symmetrical heterocyclic compound, preparation method and application thereof | 贵州大学 | 2023-09-26 | — | — | CN | claimed |
| CN-115043748-B | Long-chain fatty acid glycerol alcohol compound, preparation method and application thereof | 贵州大学 | 2023-09-26 | — | — | CN | claimed |
| CN-113773217-A | Long-chain fatty acid glycerol alcohol compound Rubracin C, preparation method and application thereof | 贵州大学 | 2021-12-10 | — | — | CN | claimed |
| CN-113679748-A | Preparation and detection method and application of saponin in conyza blinii | 重庆威迪特药业有限责任公司 | 2021-11-23 | — | — | CN | claimed |
| CN-109985145-B | Pregnancy promoting mixture for dredging pipe and preparation method thereof | 福建省南平市人民医院（福建省南平市中医院） | 2021-07-23 | — | — | CN | claimed |
| CN-112843124-A | Preparation method and quality standard of salvia miltiorrhiza formula granules | 内蒙古天奇中蒙制药股份有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-112451574-A | Honeysuckle-sweet wormwood-cape jasmine extract and preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2021-03-09 | — | — | CN | claimed |
| CN-111693641-A | Thin-layer identification method for renshu stomach-invigorating granules | 江苏弘典中药产业研究院有限公司 | 2020-09-22 | — | — | CN | claimed |
| CN-107561207-B | Thin-layer chromatography detection method for medicated leaven | 四川辅正药业股份有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-110618231-A | Preparation process and quality standard research of Baihu decoction granules | 山东省中医药研究院 | 2019-12-27 | — | — | CN | claimed |
| CN-105646413-A | Linderane compound capable of inhibiting microtubulin and preparation method and application of linderane compound capable of inhibiting microtubulin | 江西中医药大学 | 2016-06-08 | — | — | CN | claimed |
| CN-105640971-A | Application of total saponins in unripe siraitia grosvenorii fruit extract in preparation of assistant hypoglycemic drug | 广西中医药大学 | 2016-06-08 | — | — | CN | claimed |