Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13867995 | 0.94 | SIGMAR1 (0.47) | SIGMAR1MEN1KMT2ATMEM97ATM | |
| SCHEMBL13453039 | 0.81 | MEN1 (0.47) | SIGMAR1MEN1KMT2ATMEM97ATM | |
| SCHEMBL13499614 | 0.81 | SIGMAR1 (0.59) | SIGMAR1MEN1KMT2AATMPOLB | |
| SCHEMBL6369524 | 0.79 | HRH3 (0.51) | MEN1KMT2AATMPOLBDRD2 | |
| SCHEMBL20889847 | 0.78 | DRD2 (0.52) | SIGMAR1MEN1KMT2AATMPOLB | |
| SCHEMBL22549192 | 0.78 | MEN1 (0.44) | SIGMAR1MEN1KMT2ATMEM97ATM | |
| SCHEMBL14149496 | 0.78 | KDM4E (0.46) | MEN1KMT2APOLBMAPTGAA | |
| SCHEMBL15756197 | 0.77 | KMT2A (0.55) | SIGMAR1MEN1KMT2ATMEM97DRD2 | |
| SCHEMBL13255041 | 0.76 | DRD2 (0.54) | SIGMAR1MEN1KMT2AATMPOLB | |
| SCHEMBL16063012 | 0.76 | SIGMAR1 (0.47) | SIGMAR1MEN1KMT2ATMEM97ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307088-B2 | Substituted anthranilic amide derivatives and methods of use | AMGEN INC. (US) | 2007-12-11 | — | — | US | disclosed |
| US-7307088-B2 | Substituted anthranilic amide derivatives and methods of use | AMGEN INC. (US) | 2007-12-11 | — | — | US | disclosed |