SCHEMBL14352829

SCHEMBL14352829

CCCCCC(CC)c1ccc(C(=O)O)c(C)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
PPARA Q07869 2/20 0.38
RARB P10826 3/20 0.38
NR1I2 O75469 1/20 0.38
CYSLTR2 Q9NS75 1/20 0.37
CYSLTR1 Q9Y271 1/20 0.37
GRM1 Q13255 1/20 0.37
PPARG P37231 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
KAT8 Q9H7Z6 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
RECQL P46063 1/20 0.35
KMT2A Q03164 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28102719 0.89 SLC37A4 (0.40) ALDH1A1PPARARARBNR1I2CYSLTR2
SCHEMBL30438055 0.86 ALDH1A1 (0.48) ALDH1A1NR1I2CYSLTR2CYSLTR1PRSS1
SCHEMBL9998672 0.86 ALDH1A1 (0.48) ALDH1A1NR1I2CYSLTR2CYSLTR1PRSS1
SCHEMBL2807990 0.81 PDE5A (0.47) ALDH1A1PPARARARBPDE5APLK1
Hexane SCHEMBL28000698 0.80 PPARA (0.51) ALDH1A1PPARARARBPPARGKAT8
SCHEMBL2373345 0.80 SLC37A4 (0.42) ALDH1A1PPARARARBNR1I2CYSLTR2
SCHEMBL6059668 0.80 SLC37A4 (0.42) ALDH1A1PPARARARBNR1I2CYSLTR2
SCHEMBL3731183 0.79 KDM4E (0.36) ALDH1A1PPARARARBNR1I2CYSLTR2
SCHEMBL433915 0.79 ALDH1A1 (0.52) ALDH1A1CYSLTR2CYSLTR1PRSS1PRSS2
SCHEMBL8364755 0.78 ACE2 (0.44) PPARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9151849-B2 Optical fiber having scintillation quencher, a radiation sensor and a radiation detection apparatus including the optical fiber and a method of making and using the same SAINT-GOBAIN CERAMICS & PLASTICS, INC. (US) 2015-10-06 US disclosed
US-20140231656-A1 Optical Fiber Having Scintillation Quencher, a Radiation Sensor and a Radiation Detection Apparatus Including the Optical Fiber and a Method of Making and Using the Same SAINT-GOBAIN CERAMICS & PLASTICS, INC. (US) 2014-08-21 US disclosed
US-8748824-B2 Optical fiber having scintillation quencher, a radiation sensor and a radiation detection apparatus including the optical fiber and a method of making and using the same SAINT-GOBAIN CERAMICS & PLASTICS, INC. (US) 2014-06-10 US disclosed
WO-2013003621-A2 OPTICAL FIBER HAVING SCINTILLATION QUENCHER, A RADIATION SENSOR AND A RADIATION DETECTION APPARATUS INCLUDING THE OPTICAL FIBER AND A METHOD OF MAKING AND USING THE SAME SAINT-GOBAIN CERAMICS & PLASTICS, INC. (US) 2013-01-03 WO disclosed
US-20130001424-A1 OPTICAL FIBER HAVING SCINTILLATION QUENCHER, A RADIATION SENSOR AND A RADIATION DETECTION APPARATUS INCLUDING THE OPTICAL FIBER AND A METHOD OF MAKING AND USING THE SAME SAINT-GOBAIN CERAMICS & PLASTICS, INC. (US) 2013-01-03 US disclosed