Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435318 | 0.86 | CYP1B1 (0.54) | MAPTMEN1KMT2AALDH1A1CYP1B1 | |
| SCHEMBL1435433 | 0.84 | TP53 (0.53) | MAPTMEN1KMT2AALDH1A1MAOB | |
| SCHEMBL1435687 | 0.84 | MAPT (0.60) | MAPTMEN1KMT2AALDH1A1MAOB | |
| SCHEMBL1435403 | 0.84 | CYP1B1 (0.54) | MAPTMEN1KMT2AALDH1A1TNFRSF1A | |
| SCHEMBL1435414 | 0.81 | MAOB (0.56) | MAPTMEN1KMT2AALDH1A1MAOB | |
| SCHEMBL4747433 | 0.81 | PARP1 (0.78) | MAPTMEN1KMT2AALDH1A1NFKB1 | |
| SCHEMBL4747429 | 0.81 | PARP1 (0.78) | MAPTMEN1KMT2AALDH1A1NFKB1 | |
| SCHEMBL4747427 | 0.81 | PARP1 (0.78) | MAPTMEN1KMT2AALDH1A1NFKB1 | |
| SCHEMBL1435550 | 0.80 | CYP1B1 (0.57) | MAPTMEN1KMT2AALDH1A1MAOB | |
| SCHEMBL9831049 | 0.79 | RAB9A (0.66) | MAPTMEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898908-B1 | NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICAMENT | TROPHOS (FR) | 2011-03-30 | — | — | EP | claimed |
| EP-1898908-B1 | NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICAMENT | TROPHOS (FR) | 2011-03-30 | — | — | EP | disclosed |