Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.73 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.73 |
| ▸ | LTA4H | P09960 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14355080 | 0.85 | CYP11B1 (0.54) | CYP11B1CYP11B2LTA4HNPC1MAPK13 | |
| SCHEMBL7011494 | 0.79 | NOTUM (0.61) | CYP11B1CYP11B2LTA4HNPC1RAB9A | |
| Diphenylether SCHEMBL28242079 | 0.79 | NOTUM (0.67) | CYP11B1CYP11B2LTA4HNPC1RAB9A | |
| SCHEMBL14355081 | 0.78 | CYP11B1 (0.50) | CYP11B1CYP11B2LTA4HNPC1RAB9A | |
| SCHEMBL30047550 | 0.77 | LTA4H (0.63) | LTA4HNPC1RAB9ANOTUMTSHR | |
| SCHEMBL14355082 | 0.77 | NPC1 (0.56) | CYP11B1CYP11B2NPC1RAB9ACYP1A2 | |
| SCHEMBL1680381 | 0.74 | LTA4H (0.67) | LTA4HNPC1RAB9ANOTUMTSHR | |
| SCHEMBL25453590 | 0.74 | NOTUM (0.60) | CYP11B1CYP11B2NOTUMFYNCHEK1 | |
| SCHEMBL30081965 | 0.74 | NOTUM (0.60) | CYP11B1CYP11B2NOTUMFYNCHEK1 | |
| SCHEMBL2194874 | 0.74 | CYP1A2 (0.59) | CYP11B1CYP11B2LTA4HNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301029-B2 | Bipyridine Derivatives | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-7301029-B2 | Bipyridine Derivatives | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |