SCHEMBL14355567

SCHEMBL14355567

CN(C)c1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3ccc(NC(=O)CCN4CCCC4)cc23)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 20/20 1.00
▸ POT1 Q9NUX5 1/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1101549 0.96 TERT (1.00) TERTPOT1
SCHEMBL14355582 0.96 TERT (1.00) TERTPOT1
Hydrochloric Acid SCHEMBL21980540 0.95 TERT (0.98) TERTPOT1
Hydrochloric Acid SCHEMBL30693401 0.95 TERT (0.98) TERTPOT1
Hydrochloric Acid SCHEMBL30169726 0.95 TERT (0.98) TERTPOT1
SCHEMBL31237519 0.94 TERT (0.91) TERTPOT1
SCHEMBL14355571 0.89 TERT (1.00) TERT
SCHEMBL14355576 0.87 TERT (1.00) TERT
SCHEMBL14355607 0.87 TERT (1.00) TERTPOT1
SCHEMBL14355621 0.87 TERT (1.00) TERTPOT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7300930-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-11-27 — — US disclosed
US-7300930-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-11-27 — — US disclosed
US-7160896-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-01-09 — — US disclosed
US-7160896-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-01-09 — — US disclosed
Send feedback