SCHEMBL1101549

SCHEMBL1101549

CN(C)c1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 20/20 1.00
▸ POT1 Q9NUX5 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30693401 0.99 TERT (0.98) TERTPOT1
Hydrochloric Acid SCHEMBL21980540 0.99 TERT (0.98) TERTPOT1
Hydrochloric Acid SCHEMBL30169726 0.99 TERT (0.98) TERTPOT1
SCHEMBL14355567 0.96 TERT (1.00) TERTPOT1
SCHEMBL31237519 0.95 TERT (0.91) TERTPOT1
SCHEMBL14355582 0.92 TERT (1.00) TERTPOT1
SCHEMBL14355607 0.90 TERT (1.00) TERTPOT1
SCHEMBL14355621 0.90 TERT (1.00) TERTPOT1
SCHEMBL13989201 0.89 TERT (0.81) TERTPOT1
SCHEMBL14355628 0.87 TERT (1.00) TERTPOT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250281502-A1 NEW DRUG APPLICATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2025-09-11 — — US claimed
WO-2024254465-A2 METHODS FOR PROMOTING EXPANSION OF HUMAN CD34+ CELLS IN VIVO AND FOR PROMOTING NEURAL REGENERATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-12-12 — — WO claimed
CN-118033105-A Method for screening G-quadruplex ligand 中国科学院化学研究所 2024-05-14 — — CN claimed
US-20240148688-A1 METHODS FOR TREATING AND AMELIORATING CANCER UNIV CALIFORNIA (US) 2024-05-09 — — US claimed
EP-4362943-A2 NEW DRUG APPLICATION Centre National de la Recherche Scientifique (FR) 2024-05-08 — — EP claimed
US-20240108734-A1 METHODS FOR TREATING AND AMELIORATING CANCER UNIV CALIFORNIA (US) 2024-04-04 — — US claimed
WO-2023245207-A2 COMPOSITIONS AND METHODS FOR DETECTION AND TREATMENT OF CANINE CANCERS THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) 2023-12-21 — — WO claimed
EP-4284519-A1 METHODS FOR TREATING AND AMELIORATING CANCER The Regents of the University of California (US) 2023-12-06 — — EP claimed
EP-4281560-A1 METHODS FOR TREATING AND AMELIORATING CANCER The Regents of the University of California (US) 2023-11-29 — — EP claimed
CN-116829142-A Methods for treating and ameliorating cancer 加利福尼亚大学董事会 2023-09-29 — — CN claimed
WO-2023275369-A2 NEW DRUG APPLICATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-01-05 — — WO claimed
WO-2022165398-A1 METHODS FOR TREATING AND AMELIORATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-04 — — WO claimed
US-12534499-B2 Mesophilic argonaute systems and uses thereof THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-01-27 — — US disclosed
US-12442000-B2 Use of telomerase inhibitors for the treatment of myeloproliferative disorders and myeloproliferative neoplasms GERON CORPORATION (US) 2025-10-14 — — US disclosed
US-12435055-B2 3-methylideneoxan-4-one compounds and substituted derivates thereof as inhibitors of telomerase NORTHWESTERN UNIVERSITY (US) 2025-10-07 — — US disclosed
US-20250281502-A1 NEW DRUG APPLICATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2025-09-11 — — US disclosed
US-7160896-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-01-09 — — US disclosed
WO-2006124904-A2 CANCER TREATMENT BY COMBINED INHIBITION OF TELOMERASE AND HSP90 ACTIVITIES GERON CORPORATION (US) 2006-11-23 — — WO disclosed
WO-2006113426-A2 CANCER TREATMENT BY COMBINED INHIBITION OF TELOMERASE AND TUBULIN ACTIVITIES GERON CORPORATION (US) 2006-10-26 — — WO disclosed
WO-2006113470-A2 CANCER TREATMENT BY COMBINED INHIBITION OF PROTEASOME AND TELOMERASE ACTIVITIES GERON CORPORATION (US) 2006-10-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534499-B2 Mesophilic argonaute systems and uses thereof RNASE1, AGO2, RNASEH1 TERT 857/4885POT1 1063/4885
US-12435055-B2 3-methylideneoxan-4-one compounds and substituted derivates thereof as inhibitors of telomerase TERT, POT1, TERF2 TERT 1/4885POT1 2/4885
US-20240108734-A1 METHODS FOR TREATING AND AMELIORATING CANCER FLT3, MCL1, ABL1 TERT 38/4885POT1 1009/4885
US-20240148688-A1 METHODS FOR TREATING AND AMELIORATING CANCER ABL1, FLT3, MCL1 TERT 20/4885POT1 446/4885
US-12442000-B2 Use of telomerase inhibitors for the treatment of myeloproliferative disorders and myeloproliferative neoplasms TERT, POT1, MPL TERT 1/4885POT1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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