Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24760234 | 1.00 | FOLH1 (0.43) | FOLH1NAALAD2MEN1KMT2AFAAH | |
| SCHEMBL21138536 | 0.82 | NAALAD2 (0.41) | FOLH1NAALAD2ALDH1A1GABRR1CYP1A2 | |
| SCHEMBL23873825 | 0.82 | MEN1 (0.39) | FOLH1NAALAD2MEN1KMT2AFAAH | |
| SCHEMBL25633073 | 0.81 | MEN1 (0.42) | MEN1KMT2AFAAHMAPK1ALDH1A1 | |
| SCHEMBL25633074 | 0.81 | MEN1 (0.42) | MEN1KMT2AFAAHMAPK1ALDH1A1 | |
| SCHEMBL16768832 | 0.80 | NAALAD2 (0.39) | FOLH1NAALAD2FAAHALDH1A1GABRR1 | |
| SCHEMBL27261680 | 0.79 | SMN1; SMN2 (0.48) | MEN1KMT2AFAAHMAPK1ALDH1A1 | |
| SCHEMBL24183930 | 0.79 | MME (0.46) | FOLH1NAALAD2MEN1KMT2AALDH1A1 | |
| SCHEMBL17300185 | 0.78 | GABRR1 (0.41) | FOLH1NAALAD2LMNAGABRR1CYP1A2 | |
| SCHEMBL9947548 | 0.78 | GABRR1 (0.41) | FOLH1NAALAD2LMNAGABRR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SEAGEN INC (US) | 2023-06-08 | — | — | US | disclosed |
| US-7300948-B2 | Alkynyl compounds as non nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SSB, UACA, CDA | FOLH1 160/4885NAALAD2 772/4885MEN1 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.