Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14355656 | 0.82 | FOLH1 (0.43) | NAALAD2FOLH1MMEGABRR1CYP1A2 | |
| SCHEMBL24760234 | 0.82 | FOLH1 (0.43) | NAALAD2FOLH1MMEGABRR1CYP1A2 | |
| SCHEMBL16768832 | 0.77 | NAALAD2 (0.39) | NAALAD2FOLH1MMEGABRR1CYP1A2 | |
| SCHEMBL24183930 | 0.75 | MME (0.46) | NAALAD2FOLH1MMEALDH1A1 | |
| SCHEMBL17300185 | 0.75 | GABRR1 (0.41) | NAALAD2FOLH1GABRR1CYP1A2ENPEP | |
| SCHEMBL9947548 | 0.75 | GABRR1 (0.41) | NAALAD2FOLH1GABRR1CYP1A2ENPEP | |
| SCHEMBL19352706 | 0.75 | GABRR1 (0.41) | NAALAD2FOLH1GABRR1CYP1A2ENPEP | |
| SCHEMBL26207795 | 0.74 | NAALAD2 (0.46) | NAALAD2FOLH1MMEALDH1A1BLM | |
| SCHEMBL23179962 | 0.74 | POLB (0.51) | NAALAD2FOLH1GABRR1CYP1A2ALDH1A1 | |
| SCHEMBL10020473 | 0.74 | CA2 (0.53) | NAALAD2FOLH1MMECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190185455-A1 | Substituted Pyrrolidine Amides I | GRUENENTHAL GMBH (DE) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185455-A1 | Substituted Pyrrolidine Amides I | NR3C1, NR3C2, NR5A1 | NAALAD2 1108/4885FOLH1 1369/4885MME 2945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.