Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | XPNPEP2 | O43895 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14355657 | 0.89 | LMNA (0.59) | SMN1; SMN2MEN1KMT2ALMNAPKM | |
| SCHEMBL24567584 | 0.87 | LMNA (0.45) | SMN1; SMN2MEN1KMT2ALMNAXPNPEP2 | |
| SCHEMBL14355655 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2ALMNAPKM | |
| SCHEMBL24568858 | 0.84 | GAA (0.54) | SMN1; SMN2MEN1KMT2ALMNAXPNPEP2 | |
| SCHEMBL13560112 | 0.80 | LMNA (0.51) | SMN1; SMN2LMNAPOLBGAA | |
| SCHEMBL24851658 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2APKMPOLB | |
| SCHEMBL24567568 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2APKMCYP2C9 | |
| SCHEMBL2307715 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2ALMNAPKM | |
| SCHEMBL12448071 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2ALMNAPKM | |
| SCHEMBL12448168 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2APKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300948-B2 | Alkynyl compounds as non nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-11-27 | — | — | US | disclosed |