Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14444902 | 0.83 | CETP (0.43) | KMT2AMEN1NPSR1HSD17B10RAB9A | |
| SCHEMBL6857302 | 0.79 | KMT2A (0.65) | KMT2AMEN1TP53POLBNPSR1 | |
| SCHEMBL13236107 | 0.78 | RAB9A (0.62) | POLBHSD17B10RAB9AMAPTNPC1 | |
| SCHEMBL5914915 | 0.78 | DHODH (0.57) | KMT2AMEN1TP53POLBNPSR1 | |
| SCHEMBL5914914 | 0.78 | DHODH (0.57) | KMT2AMEN1TP53POLBNPSR1 | |
| SCHEMBL4210466 | 0.77 | KMT2A (0.62) | KMT2AMEN1TP53POLBNPSR1 | |
| SCHEMBL4938228 | 0.77 | KMT2A (0.62) | KMT2AMEN1TP53POLBNPSR1 | |
| SCHEMBL29651063 | 0.77 | KMT2A (0.62) | KMT2AMEN1TP53POLBNPSR1 | |
| SCHEMBL2935482 | 0.77 | KMT2A (0.68) | KMT2AMEN1TP53POLBNPSR1 | |
| SCHEMBL27665991 | 0.77 | KMT2A (0.62) | KMT2AMEN1TP53POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297820-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-11-20 | — | — | US | disclosed |