Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14355943 | 0.83 | KMT2A (0.56) | ALDH1A1KMT2AL3MBTL1GAAHPGD | |
| SCHEMBL28346162 | 0.79 | CETP (0.54) | CETPALDH1A1KMT2AHDAC3HDAC1 | |
| SCHEMBL28277559 | 0.76 | MAPT (0.62) | ALDH1A1KMT2AHDAC3HDAC1L3MBTL1 | |
| SCHEMBL11218848 | 0.76 | ALDH1A1 (0.63) | CETPALDH1A1KMT2AHDAC3HDAC1 | |
| SCHEMBL13236107 | 0.73 | RAB9A (0.62) | ALDH1A1HPGDHSD17B10MAPK1NPC1 | |
| SCHEMBL28693497 | 0.73 | CETP (0.48) | CETPALDH1A1KMT2AHDAC3HDAC1 | |
| SCHEMBL948297 | 0.72 | ADRA2A (0.47) | CETPALDH1A1HDAC3HDAC1L3MBTL1 | |
| SCHEMBL14383870 | 0.70 | ADRA2A (0.46) | CETPALDH1A1HDAC3HDAC1L3MBTL1 | |
| SCHEMBL23302280 | 0.69 | ADRA2A (0.45) | CETPALDH1A1HDAC3HDAC1L3MBTL1 | |
| SCHEMBL17325503 | 0.69 | ADRA1D (0.53) | CETPALDH1A1KMT2AL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250525-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-07-31 | — | — | US | disclosed |