Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435643 | 1.00 | ALDH1A1 (0.61) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL1435417 | 0.91 | MAPT (0.52) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL1435601 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL1435442 | 0.82 | MAPT (0.56) | ALDH1A1MAPTRAB9AKMT2AGAA | |
| SCHEMBL1435501 | 0.82 | MAPT (0.56) | ALDH1A1MAPTRAB9AKMT2AGAA | |
| SCHEMBL1435419 | 0.78 | MAPT (0.48) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL1435482 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL4094409 | 0.69 | MEN1 (0.73) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL4094410 | 0.69 | MEN1 (0.73) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL4098407 | 0.68 | MEN1 (0.68) | ALDH1A1MAPTRAB9AKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898908-B1 | NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICAMENT | TROPHOS (FR) | 2011-03-30 | — | — | EP | claimed |