Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435596 | 1.00 | ALDH1A1 (0.61) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL1435417 | 0.91 | MAPT (0.52) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL1435601 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL1435442 | 0.82 | MAPT (0.56) | ALDH1A1MAPTRAB9AKMT2AGAA | |
| SCHEMBL1435501 | 0.82 | MAPT (0.56) | ALDH1A1MAPTRAB9AKMT2AGAA | |
| SCHEMBL1435419 | 0.78 | MAPT (0.48) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL1435482 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL4094409 | 0.69 | MEN1 (0.73) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL4094410 | 0.69 | MEN1 (0.73) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL4098407 | 0.68 | MEN1 (0.68) | ALDH1A1MAPTRAB9AKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898908-B1 | NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICAMENT | TROPHOS (FR) | 2011-03-30 | — | — | EP | claimed |
| US-20090203747-A1 | NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICINE | TROPHOS PARC SCIENTIFIQUE LUMINY (FR) | 2009-08-13 | — | — | US | claimed |
| US-20090203747-A1 | NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICINE | TROPHOS PARC SCIENTIFIQUE LUMINY (FR) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203747-A1 | NOVEL CHEMICAL COMPOUNDS AND THE USES THEREOF AS A MEDICINE | NLN, NQO1, APP | ALDH1A1 625/4885MAPT 31/4885RAB9A 2239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.