Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 14/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14355836 | 0.84 | MAPK1 (0.60) | MAPTNPSR1L3MBTL1GAAPOLB | |
| SCHEMBL7537046 | 0.84 | CHEK1 (0.54) | CHEK1ADRB1MAPTNPSR1L3MBTL1 | |
| SCHEMBL1646808 | 0.82 | CHEK1 (0.55) | CHEK1ADRB1 | |
| SCHEMBL5558994 | 0.80 | POLB (0.66) | CHEK1MAPTNPSR1L3MBTL1GAA | |
| SCHEMBL1646812 | 0.78 | NPSR1 (0.51) | CHEK1MAPTNPSR1L3MBTL1GAA | |
| SCHEMBL5563711 | 0.78 | SMN1; SMN2 (0.72) | CHEK1MAPTNPSR1GAAPOLB | |
| SCHEMBL14356004 | 0.78 | KCNQ2 (0.55) | CHEK1MAPTNPSR1L3MBTL1GAA | |
| SCHEMBL6991512 | 0.78 | CHEK1 (0.49) | CHEK1ADRB1MAPTNPSR1L3MBTL1 | |
| SCHEMBL7833448 | 0.77 | CHEK1 (0.50) | CHEK1NPSR1L3MBTL1GAA | |
| SCHEMBL8142012 | 0.77 | MEN1 (0.56) | MAPTNPSR1L3MBTL1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |