Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 17/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1646808 | 0.86 | CHEK1 (0.55) | CHEK1 | |
| SCHEMBL7537046 | 0.82 | CHEK1 (0.54) | NPSR1MAPTL3MBTL1CHEK1 | |
| SCHEMBL14356004 | 0.82 | KCNQ2 (0.55) | NPSR1MAPTL3MBTL1GAACHEK1 | |
| SCHEMBL5558994 | 0.81 | POLB (0.66) | NPSR1MAPTL3MBTL1GAACHEK1 | |
| SCHEMBL5563711 | 0.79 | SMN1; SMN2 (0.72) | NPSR1MAPTGAACHEK1 | |
| SCHEMBL1643882 | 0.79 | ALDH1A1 (0.51) | NPSR1L3MBTL1 | |
| SCHEMBL14356002 | 0.78 | CHEK1 (0.54) | NPSR1MAPTL3MBTL1GAACHEK1 | |
| SCHEMBL7833448 | 0.78 | CHEK1 (0.50) | NPSR1L3MBTL1GAACHEK1 | |
| SCHEMBL6991512 | 0.76 | CHEK1 (0.49) | NPSR1MAPTL3MBTL1GAACHEK1 | |
| SCHEMBL20910885 | 0.75 | ALDH1A1 (0.68) | NPSR1MAPTL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4665239-B2 | — | — | 2011-04-06 | — | — | JP | claimed |
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |
| CN-1297442-A | 5-aminoindeno [1,2-c] pyrazol-4-ones as anti-cancer and anti-proliferative agents | DU PONT PHARM CO (US) | 2001-05-30 | — | — | CN | disclosed |