Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.49 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.49 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5558994 | 0.86 | POLB (0.66) | KCNQ2MAPTNPSR1L3MBTL1GAA | |
| SCHEMBL14355837 | 0.85 | MAPK1 (0.57) | KCNQ2MAPTNPSR1L3MBTL1GAA | |
| SCHEMBL1646812 | 0.82 | NPSR1 (0.51) | MAPTNPSR1L3MBTL1GAACHEK1 | |
| SCHEMBL7537046 | 0.81 | CHEK1 (0.54) | MAPTNPSR1L3MBTL1CHEK1 | |
| SCHEMBL19977049 | 0.80 | ALDH1A1 (0.55) | KCNQ2MAPTNPSR1GAAMAPK1 | |
| SCHEMBL14356046 | 0.80 | GAA (0.78) | KCNQ2MAPTNPSR1L3MBTL1GAA | |
| SCHEMBL1646808 | 0.80 | CHEK1 (0.55) | CHEK1 | |
| SCHEMBL13062775 | 0.78 | ADRB1 (0.54) | MAPTHSD17B10ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL14356002 | 0.78 | CHEK1 (0.54) | MAPTNPSR1L3MBTL1GAAPOLB | |
| SCHEMBL5336322 | 0.78 | ALDH1A1 (0.52) | KCNQ2MAPTNPSR1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |