Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14356008 | 0.78 | HTR1A (0.50) | HTR1ASLC6A2SLC6A4SLC6A3ADRB1 | |
| SCHEMBL335802 | 0.74 | HTR1A (0.73) | HTR1ASLC6A2SLC6A4SLC6A3ADRB1 | |
| SCHEMBL31561598 | 0.74 | HTR1A (0.73) | HTR1ASLC6A2SLC6A4SLC6A3ADRB1 | |
| SCHEMBL28078181 | 0.74 | HTR1A (0.73) | HTR1ASLC6A2SLC6A4SLC6A3ADRB1 | |
| SCHEMBL6164646 | 0.73 | HTR1A (0.60) | HTR1ASLC6A2SLC6A4SLC6A3ADRB1 | |
| Hydrochloric Acid SCHEMBL7927336 | 0.73 | HTR1A (0.71) | HTR1ASLC6A2SLC6A4SLC6A3ADRB1 | |
| Hydrochloric Acid SCHEMBL7982587 | 0.73 | HTR1A (0.71) | HTR1ASLC6A2SLC6A4SLC6A3ADRB1 | |
| Piperazine SCHEMBL28217787 | 0.73 | HTR1A (0.71) | HTR1ASLC6A2SLC6A4SLC6A3ADRB1 | |
| SCHEMBL16814964 | 0.72 | HTR1A (0.55) | HTR1ASLC6A2SLC6A4SLC6A3ADRB1 | |
| Hydrochloric Acid SCHEMBL9654609 | 0.72 | HTR1A (0.59) | HTR1ASLC6A2SLC6A4SLC6A3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |