Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.73 |
| ▸ | HPGD | P15428 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | GAA | P10253 | 4/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | LDHB | P07195 | 1/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435725 | 1.00 | ALDH1A1 (0.73) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL13567515 | 1.00 | ALDH1A1 (0.73) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL12817961 | 0.91 | ALDH1A1 (0.68) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL1435370 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL1435373 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL8298573 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL1435732 | 0.76 | LDHA (0.43) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL6720913 | 0.73 | MAPT (0.75) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL17124156 | 0.69 | ALDH1A1 (0.60) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL12818316 | 0.68 | POLB (0.67) | ALDH1A1HPGDMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802297-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASE CAUSED BY YERSINIA SPP INFECTION | BURNHAM INST (US) | 2011-03-30 | — | — | EP | claimed |