⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18075842 | 0.74 | — | — | |
| SCHEMBL14909578 | 0.70 | USP2 (0.31) | — | |
| SCHEMBL22346155 | 0.68 | — | — | |
| SCHEMBL15910863 | 0.67 | USP2 (0.32) | — | |
| SCHEMBL1062985 | 0.66 | LMNA (0.39) | — | |
| SCHEMBL22582036 | 0.65 | PKM (0.34) | — | |
| SCHEMBL17074177 | 0.64 | — | — | |
| SCHEMBL1139842 | 0.61 | FFAR3 (0.35) | — | |
| SCHEMBL17435799 | 0.60 | — | — | |
| SCHEMBL14910753 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723737-A1 | BRIDGED BICYCLIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | Kyorin Pharmaceutical Co., Ltd. (JP) | 2014-04-30 | — | — | EP | disclosed |
| WO-2013003383-A1 | BRIDGED BICYCLIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2013-01-03 | — | — | WO | disclosed |