Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30040149 | 1.00 | AR (0.44) | ARCA1CA2CA7CA9 | |
| SCHEMBL31347528 | 0.78 | CA1 (0.46) | ARCA1CA2CA7CA9 | |
| SCHEMBL6558441 | 0.78 | CA1 (0.46) | ARCA1CA2CA7CA9 | |
| SCHEMBL255270 | 0.77 | CA1 (0.55) | ARCA1CA2CA7CA9 | |
| SCHEMBL30093322 | 0.77 | CA1 (0.55) | ARCA1CA2CA7CA9 | |
| SCHEMBL28228661 | 0.77 | CA1 (0.55) | ARCA1CA2CA7CA9 | |
| SCHEMBL6234577 | 0.77 | CA1 (0.44) | ARCA1CA2CA7CA9 | |
| SCHEMBL27708857 | 0.74 | CA1 (0.46) | CA1CA2CA7CA9CA12 | |
| SCHEMBL30039455 | 0.74 | AR (0.40) | ARCA1CA2CA7CA9 | |
| SCHEMBL21033757 | 0.74 | AR (0.40) | ARCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111372936-B | Mcl-1 selective inhibitors, their preparation and use | 北京赛林泰医药技术有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-111372936-A | Mcl-1 selective inhibitors, their preparation and use | 北京赛林泰医药技术有限公司 | 2020-07-03 | — | — | CN | disclosed |
| WO-2019101144-A1 | SELECTIVE MCL-1 INHIBITOR AND PREPARATION AND USE THEREOF | 北京赛林泰医药技术有限公司 | 2019-05-31 | — | — | WO | disclosed |
| US-9447029-B2 | Fluorinated arylalkylaminocarboxamide derivatives | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2016-09-20 | — | — | US | disclosed |
| EP-2723710-B1 | FLUORINATED ARYLALKYLAMINOCARBOXAMIDE DERIVATIVES | NEWRON PHARM SPA (IT) | 2016-08-10 | — | — | EP | disclosed |
| EP-2723710-A1 | FLUORINATED ARYLALKYLAMINOCARBOXAMIDE DERIVATIVES | Newron Pharmaceuticals S.p.A. (IT) | 2014-04-30 | — | — | EP | disclosed |
| US-20140088074-A1 | FLUORINATED ARYLALKYLAMINOCARBOXAMIDE DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2014-03-27 | — | — | US | disclosed |
| WO-2013000651-A1 | FLUORINATED ARYLALKYLAMINOCARBOXAMIDE DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2013-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088074-A1 | FLUORINATED ARYLALKYLAMINOCARBOXAMIDE DERIVATIVES | CACNA1E, CACNA1B, CACNA1A | AR 678/4885CA1 2189/4885CA2 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.