Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 9/20 | 0.59 |
| ▸ | MC4R | P32245 | 9/20 | 0.59 |
| ▸ | YAP1 | P46937 | 7/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14360771 | 1.00 | MC1R (0.59) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL1310689 | 0.97 | MC1R (0.58) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL20450359 | 0.97 | MC1R (0.58) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL20450426 | 0.93 | MC1R (0.54) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL20450428 | 0.93 | MC1R (0.54) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL14360686 | 0.92 | MC1R (0.51) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL20450379 | 0.89 | MC1R (0.59) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL1311611 | 0.89 | MC1R (0.59) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL1310472 | 0.88 | MC1R (0.60) | MC1RMC4RMC5RMC3RHTR3E | |
| SCHEMBL20450366 | 0.88 | MC1R (0.63) | MC1RMC4RYAP1MC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981952-B2 | Oxazetidine derivatives, process for preparing them and use in human medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2018-05-29 | — | — | US | claimed |
| US-9981952-B2 | Oxazetidine derivatives, process for preparing them and use in human medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2018-05-29 | — | — | US | disclosed |
| EP-2726478-B1 | OXAZETIDINE DERIVATIVES, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2017-01-11 | — | — | EP | disclosed |
| US-20160237065-A1 | OXAZETIDINE DERIVATIVES, PROCESS FOR PREPARING THEM AND USE IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-08-18 | — | — | US | disclosed |
| US-9353083-B2 | Oxazetidine derivatives, process for preparing them and use in human medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-05-31 | — | — | US | disclosed |
| US-20140228342-A1 | OXAZETIDINE DERIVATIVES, PROCESS FOR PREPARING THEM AND USE IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2014-08-14 | — | — | US | disclosed |
| EP-2726478-A1 | OXAZETIDINE DERIVATIVES, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2014-05-07 | — | — | EP | disclosed |
| WO-2013001030-A1 | OXAZETIDINE DERIVATIVES, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237065-A1 | OXAZETIDINE DERIVATIVES, PROCESS FOR PREPARING THEM AND USE IN HUMAN MEDICINE AND IN COSMETICS | MC1R, MCHR1, MCHR2 | MC1R 1/4885MC4R 31/4885YAP1 2921/4885 |
| US-20140228342-A1 | OXAZETIDINE DERIVATIVES, PROCESS FOR PREPARING THEM AND USE IN HUMAN MEDICINE AND IN COSMETICS | MC1R, MCHR1, MCHR2 | MC1R 1/4885MC4R 33/4885YAP1 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.