Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 9/20 | 0.58 |
| ▸ | MC4R | P32245 | 9/20 | 0.58 |
| ▸ | YAP1 | P46937 | 7/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310689 | 1.00 | MC1R (0.58) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL14360239 | 0.97 | MC1R (0.59) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL14360771 | 0.97 | MC1R (0.59) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL20450426 | 0.95 | MC1R (0.54) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL20450428 | 0.95 | MC1R (0.54) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL14360686 | 0.89 | MC1R (0.51) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL20450379 | 0.88 | MC1R (0.59) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL1311611 | 0.88 | MC1R (0.59) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL1310472 | 0.87 | MC1R (0.60) | MC1RMC4RMC5RMC3RHTR3E | |
| SCHEMBL1313222 | 0.86 | MC1R (0.61) | MC1RMC4RYAP1MC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-B1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2018-08-08 | — | — | EP | claimed |
| EP-2342194-B1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2018-08-08 | — | — | EP | disclosed |