Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 9/20 | 0.51 |
| ▸ | MC4R | P32245 | 9/20 | 0.51 |
| ▸ | YAP1 | P46937 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14360239 | 0.92 | MC1R (0.59) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL14360771 | 0.92 | MC1R (0.59) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL1310689 | 0.89 | MC1R (0.58) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL20450359 | 0.89 | MC1R (0.58) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL20450426 | 0.85 | MC1R (0.54) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL20450428 | 0.85 | MC1R (0.54) | MC1RMC4RYAP1MC5RMC3R | |
| SCHEMBL1311611 | 0.82 | MC1R (0.59) | MC1RMC4RYAP1KMT2AMC5R | |
| SCHEMBL20450379 | 0.82 | MC1R (0.59) | MC1RMC4RYAP1KMT2AMC5R | |
| SCHEMBL1310472 | 0.81 | MC1R (0.60) | MC1RMC4RMC5RMC3R | |
| SCHEMBL1310154 | 0.80 | MC1R (0.63) | MC1RMC4RYAP1MC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2726478-A1 | OXAZETIDINE DERIVATIVES, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2014-05-07 | — | — | EP | disclosed |
| WO-2013001030-A1 | OXAZETIDINE DERIVATIVES, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-01-03 | — | — | WO | disclosed |